Cuprenil
Brand names,
Cuprenil
Analogs
Cuprenil
Brand Names Mixture
Cuprenil
Chemical_Formula
C5H11NO2S
Cuprenil
RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Cuprenil
fda sheet
Cuprenil
msds (material safety sheet)
Cuprenil
Synthesis Reference
No information avaliable
Cuprenil
Molecular Weight
149.212 g/mol
Cuprenil
Melting Point
198.5 oC
Cuprenil
H2O Solubility
1.11E+005 mg/L
Cuprenil
State
Solid
Cuprenil
LogP
-2.09
Cuprenil
Dosage Forms
Capsule; Tablet
Cuprenil
Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Cuprenil
Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Cuprenil
Absorption
rapidly but incompletely
Cuprenil
side effects and Toxicity
No information avaliable
Cuprenil
Patient Information
No information avaliable
Cuprenil
Organisms Affected
Humans and other mammals