Artamine
Brand names,
Artamine
Analogs
Artamine
Brand Names Mixture
Artamine
Chemical_Formula
C5H11NO2S
Artamine
RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Artamine
fda sheet
Artamine
msds (material safety sheet)
Artamine
Synthesis Reference
No information avaliable
Artamine
Molecular Weight
149.212 g/mol
Artamine
Melting Point
198.5 oC
Artamine
H2O Solubility
1.11E+005 mg/L
Artamine
State
Solid
Artamine
LogP
-2.09
Artamine
Dosage Forms
Capsule; Tablet
Artamine
Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Artamine
Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Artamine
Absorption
rapidly but incompletely
Artamine
side effects and Toxicity
No information avaliable
Artamine
Patient Information
No information avaliable
Artamine
Organisms Affected
Humans and other mammals