Mercaptyl
Brand names,
Mercaptyl
Analogs
Mercaptyl
Brand Names Mixture
Mercaptyl
Chemical_Formula
C5H11NO2S
Mercaptyl
RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
Mercaptyl
fda sheet
Mercaptyl
msds (material safety sheet)
Mercaptyl
Synthesis Reference
No information avaliable
Mercaptyl
Molecular Weight
149.212 g/mol
Mercaptyl
Melting Point
198.5 oC
Mercaptyl
H2O Solubility
1.11E+005 mg/L
Mercaptyl
State
Solid
Mercaptyl
LogP
-2.09
Mercaptyl
Dosage Forms
Capsule; Tablet
Mercaptyl
Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
Mercaptyl
Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
Mercaptyl
Absorption
rapidly but incompletely
Mercaptyl
side effects and Toxicity
No information avaliable
Mercaptyl
Patient Information
No information avaliable
Mercaptyl
Organisms Affected
Humans and other mammals