PharmacyCodes



Penicillaminum [INN-Latin] en es it fr

Penicillaminum [INN-Latin] Brand names, Penicillaminum [INN-Latin] Analogs

Penicillaminum [INN-Latin] Brand Names Mixture

  • No information avaliable

Penicillaminum [INN-Latin] Chemical_Formula

C5H11NO2S

Penicillaminum [INN-Latin] RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Penicillaminum [INN-Latin] fda sheet

Penicillaminum_[INN-Latin] FDA

Penicillaminum [INN-Latin] msds (material safety sheet)

Penicillaminum_[INN-Latin] MSDS

Penicillaminum [INN-Latin] Synthesis Reference

No information avaliable

Penicillaminum [INN-Latin] Molecular Weight

149.212 g/mol

Penicillaminum [INN-Latin] Melting Point

198.5 oC

Penicillaminum [INN-Latin] H2O Solubility

1.11E+005 mg/L

Penicillaminum [INN-Latin] State

Solid

Penicillaminum [INN-Latin] LogP

-2.09

Penicillaminum [INN-Latin] Dosage Forms

Capsule; Tablet

Penicillaminum [INN-Latin] Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Penicillaminum [INN-Latin] Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Penicillaminum [INN-Latin] Absorption

rapidly but incompletely

Penicillaminum [INN-Latin] side effects and Toxicity

No information avaliable

Penicillaminum [INN-Latin] Patient Information

No information avaliable

Penicillaminum [INN-Latin] Organisms Affected

Humans and other mammals