beta,beta-Dimethylcysteine
Brand names,
beta,beta-Dimethylcysteine
Analogs
beta,beta-Dimethylcysteine
Brand Names Mixture
beta,beta-Dimethylcysteine
Chemical_Formula
C5H11NO2S
beta,beta-Dimethylcysteine
RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
beta,beta-Dimethylcysteine
fda sheet
beta,beta-Dimethylcysteine
msds (material safety sheet)
beta,beta-Dimethylcysteine
Synthesis Reference
No information avaliable
beta,beta-Dimethylcysteine
Molecular Weight
149.212 g/mol
beta,beta-Dimethylcysteine
Melting Point
198.5 oC
beta,beta-Dimethylcysteine
H2O Solubility
1.11E+005 mg/L
beta,beta-Dimethylcysteine
State
Solid
beta,beta-Dimethylcysteine
LogP
-2.09
beta,beta-Dimethylcysteine
Dosage Forms
Capsule; Tablet
beta,beta-Dimethylcysteine
Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
beta,beta-Dimethylcysteine
Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
beta,beta-Dimethylcysteine
Absorption
rapidly but incompletely
beta,beta-Dimethylcysteine
side effects and Toxicity
No information avaliable
beta,beta-Dimethylcysteine
Patient Information
No information avaliable
beta,beta-Dimethylcysteine
Organisms Affected
Humans and other mammals