L-Penicillamine 99.5+
Brand names,
L-Penicillamine 99.5+
Analogs
L-Penicillamine 99.5+
Brand Names Mixture
L-Penicillamine 99.5+
Chemical_Formula
C5H11NO2S
L-Penicillamine 99.5+
RX_link
http://www.rxlist.com/cgi/generic3/penicillamine.htm
L-Penicillamine 99.5+
fda sheet
L-Penicillamine 99.5+
msds (material safety sheet)
L-Penicillamine 99.5+
Synthesis Reference
No information avaliable
L-Penicillamine 99.5+
Molecular Weight
149.212 g/mol
L-Penicillamine 99.5+
Melting Point
198.5 oC
L-Penicillamine 99.5+
H2O Solubility
1.11E+005 mg/L
L-Penicillamine 99.5+
State
Solid
L-Penicillamine 99.5+
LogP
-2.09
L-Penicillamine 99.5+
Dosage Forms
Capsule; Tablet
L-Penicillamine 99.5+
Indication
For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis
L-Penicillamine 99.5+
Pharmacology
Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.
L-Penicillamine 99.5+
Absorption
rapidly but incompletely
L-Penicillamine 99.5+
side effects and Toxicity
No information avaliable
L-Penicillamine 99.5+
Patient Information
No information avaliable
L-Penicillamine 99.5+
Organisms Affected
Humans and other mammals