Hexachlorophene
Brand names,
Hexachlorophene
Analogs
Hexachlorophene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexachlorophene
Chemical_Formula
C13H6Cl6O2
Hexachlorophene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexachlorophene
fda sheet
Hexachlorophene
msds (material safety sheet)
Hexachlorophene
Synthesis Reference
No information avaliable
Hexachlorophene
Molecular Weight
406.902 g/mol
Hexachlorophene
Melting Point
166.5 oC (boiling point)
Hexachlorophene
H2O Solubility
140 mg/L
Hexachlorophene
State
Liquid
Hexachlorophene
LogP
6.941
Hexachlorophene
Dosage Forms
Liquid
Hexachlorophene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexachlorophene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexachlorophene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexachlorophene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexachlorophene
Patient Information
No information avaliable
Hexachlorophene
Organisms Affected
Enteric bacteria and other eubacteria