Trichlorophene
Brand names,
Trichlorophene
Analogs
Trichlorophene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Trichlorophene
Chemical_Formula
C13H6Cl6O2
Trichlorophene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Trichlorophene
fda sheet
Trichlorophene
msds (material safety sheet)
Trichlorophene
Synthesis Reference
No information avaliable
Trichlorophene
Molecular Weight
406.902 g/mol
Trichlorophene
Melting Point
166.5 oC (boiling point)
Trichlorophene
H2O Solubility
140 mg/L
Trichlorophene
State
Liquid
Trichlorophene
LogP
6.941
Trichlorophene
Dosage Forms
Liquid
Trichlorophene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Trichlorophene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Trichlorophene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Trichlorophene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Trichlorophene
Patient Information
No information avaliable
Trichlorophene
Organisms Affected
Enteric bacteria and other eubacteria