Hexafen
Brand names,
Hexafen
Analogs
Hexafen
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexafen
Chemical_Formula
C13H6Cl6O2
Hexafen
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexafen
fda sheet
Hexafen
msds (material safety sheet)
Hexafen
Synthesis Reference
No information avaliable
Hexafen
Molecular Weight
406.902 g/mol
Hexafen
Melting Point
166.5 oC (boiling point)
Hexafen
H2O Solubility
140 mg/L
Hexafen
State
Liquid
Hexafen
LogP
6.941
Hexafen
Dosage Forms
Liquid
Hexafen
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexafen
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexafen
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexafen
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexafen
Patient Information
No information avaliable
Hexafen
Organisms Affected
Enteric bacteria and other eubacteria