Exofene
Brand names,
Exofene
Analogs
Exofene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Exofene
Chemical_Formula
C13H6Cl6O2
Exofene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Exofene
fda sheet
Exofene
msds (material safety sheet)
Exofene
Synthesis Reference
No information avaliable
Exofene
Molecular Weight
406.902 g/mol
Exofene
Melting Point
166.5 oC (boiling point)
Exofene
H2O Solubility
140 mg/L
Exofene
State
Liquid
Exofene
LogP
6.941
Exofene
Dosage Forms
Liquid
Exofene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Exofene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Exofene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Exofene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Exofene
Patient Information
No information avaliable
Exofene
Organisms Affected
Enteric bacteria and other eubacteria