Hexide
Brand names,
Hexide
Analogs
Hexide
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexide
Chemical_Formula
C13H6Cl6O2
Hexide
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexide
fda sheet
Hexide
msds (material safety sheet)
Hexide
Synthesis Reference
No information avaliable
Hexide
Molecular Weight
406.902 g/mol
Hexide
Melting Point
166.5 oC (boiling point)
Hexide
H2O Solubility
140 mg/L
Hexide
State
Liquid
Hexide
LogP
6.941
Hexide
Dosage Forms
Liquid
Hexide
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexide
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexide
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexide
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexide
Patient Information
No information avaliable
Hexide
Organisms Affected
Enteric bacteria and other eubacteria