Gamophene
Brand names,
Gamophene
Analogs
Gamophene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Gamophene
Chemical_Formula
C13H6Cl6O2
Gamophene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Gamophene
fda sheet
Gamophene
msds (material safety sheet)
Gamophene
Synthesis Reference
No information avaliable
Gamophene
Molecular Weight
406.902 g/mol
Gamophene
Melting Point
166.5 oC (boiling point)
Gamophene
H2O Solubility
140 mg/L
Gamophene
State
Liquid
Gamophene
LogP
6.941
Gamophene
Dosage Forms
Liquid
Gamophene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Gamophene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Gamophene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Gamophene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Gamophene
Patient Information
No information avaliable
Gamophene
Organisms Affected
Enteric bacteria and other eubacteria