Distodin
Brand names,
Distodin
Analogs
Distodin
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Distodin
Chemical_Formula
C13H6Cl6O2
Distodin
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Distodin
fda sheet
Distodin
msds (material safety sheet)
Distodin
Synthesis Reference
No information avaliable
Distodin
Molecular Weight
406.902 g/mol
Distodin
Melting Point
166.5 oC (boiling point)
Distodin
H2O Solubility
140 mg/L
Distodin
State
Liquid
Distodin
LogP
6.941
Distodin
Dosage Forms
Liquid
Distodin
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Distodin
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Distodin
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Distodin
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Distodin
Patient Information
No information avaliable
Distodin
Organisms Affected
Enteric bacteria and other eubacteria