Fascol
Brand names,
Fascol
Analogs
Fascol
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Fascol
Chemical_Formula
C13H6Cl6O2
Fascol
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
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fda sheet
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msds (material safety sheet)
Fascol
Synthesis Reference
No information avaliable
Fascol
Molecular Weight
406.902 g/mol
Fascol
Melting Point
166.5 oC (boiling point)
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H2O Solubility
140 mg/L
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State
Liquid
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LogP
6.941
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Dosage Forms
Liquid
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Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Fascol
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Fascol
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
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side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
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Patient Information
No information avaliable
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Organisms Affected
Enteric bacteria and other eubacteria