Hexachlorophen
Brand names,
Hexachlorophen
Analogs
Hexachlorophen
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexachlorophen
Chemical_Formula
C13H6Cl6O2
Hexachlorophen
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexachlorophen
fda sheet
Hexachlorophen
msds (material safety sheet)
Hexachlorophen
Synthesis Reference
No information avaliable
Hexachlorophen
Molecular Weight
406.902 g/mol
Hexachlorophen
Melting Point
166.5 oC (boiling point)
Hexachlorophen
H2O Solubility
140 mg/L
Hexachlorophen
State
Liquid
Hexachlorophen
LogP
6.941
Hexachlorophen
Dosage Forms
Liquid
Hexachlorophen
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexachlorophen
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexachlorophen
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexachlorophen
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexachlorophen
Patient Information
No information avaliable
Hexachlorophen
Organisms Affected
Enteric bacteria and other eubacteria