Hexazinone
Brand names,
Hexazinone
Analogs
Hexazinone
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexazinone
Chemical_Formula
C13H6Cl6O2
Hexazinone
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexazinone
fda sheet
Hexazinone
msds (material safety sheet)
Hexazinone
Synthesis Reference
No information avaliable
Hexazinone
Molecular Weight
406.902 g/mol
Hexazinone
Melting Point
166.5 oC (boiling point)
Hexazinone
H2O Solubility
140 mg/L
Hexazinone
State
Liquid
Hexazinone
LogP
6.941
Hexazinone
Dosage Forms
Liquid
Hexazinone
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexazinone
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexazinone
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexazinone
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexazinone
Patient Information
No information avaliable
Hexazinone
Organisms Affected
Enteric bacteria and other eubacteria