Gamophen
Brand names,
Gamophen
Analogs
Gamophen
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Gamophen
Chemical_Formula
C13H6Cl6O2
Gamophen
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Gamophen
fda sheet
Gamophen
msds (material safety sheet)
Gamophen
Synthesis Reference
No information avaliable
Gamophen
Molecular Weight
406.902 g/mol
Gamophen
Melting Point
166.5 oC (boiling point)
Gamophen
H2O Solubility
140 mg/L
Gamophen
State
Liquid
Gamophen
LogP
6.941
Gamophen
Dosage Forms
Liquid
Gamophen
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Gamophen
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Gamophen
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Gamophen
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Gamophen
Patient Information
No information avaliable
Gamophen
Organisms Affected
Enteric bacteria and other eubacteria