Hexachlorophane
Brand names,
Hexachlorophane
Analogs
Hexachlorophane
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexachlorophane
Chemical_Formula
C13H6Cl6O2
Hexachlorophane
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexachlorophane
fda sheet
Hexachlorophane
msds (material safety sheet)
Hexachlorophane
Synthesis Reference
No information avaliable
Hexachlorophane
Molecular Weight
406.902 g/mol
Hexachlorophane
Melting Point
166.5 oC (boiling point)
Hexachlorophane
H2O Solubility
140 mg/L
Hexachlorophane
State
Liquid
Hexachlorophane
LogP
6.941
Hexachlorophane
Dosage Forms
Liquid
Hexachlorophane
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexachlorophane
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexachlorophane
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexachlorophane
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexachlorophane
Patient Information
No information avaliable
Hexachlorophane
Organisms Affected
Enteric bacteria and other eubacteria