Isobac 20
Brand names,
Isobac 20
Analogs
Isobac 20
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Isobac 20
Chemical_Formula
C13H6Cl6O2
Isobac 20
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Isobac 20
fda sheet
Isobac 20
msds (material safety sheet)
Isobac 20
Synthesis Reference
No information avaliable
Isobac 20
Molecular Weight
406.902 g/mol
Isobac 20
Melting Point
166.5 oC (boiling point)
Isobac 20
H2O Solubility
140 mg/L
Isobac 20
State
Liquid
Isobac 20
LogP
6.941
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Dosage Forms
Liquid
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Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Isobac 20
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Isobac 20
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Isobac 20
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Isobac 20
Patient Information
No information avaliable
Isobac 20
Organisms Affected
Enteric bacteria and other eubacteria