Steraskin
Brand names,
Steraskin
Analogs
Steraskin
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Steraskin
Chemical_Formula
C13H6Cl6O2
Steraskin
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Steraskin
fda sheet
Steraskin
msds (material safety sheet)
Steraskin
Synthesis Reference
No information avaliable
Steraskin
Molecular Weight
406.902 g/mol
Steraskin
Melting Point
166.5 oC (boiling point)
Steraskin
H2O Solubility
140 mg/L
Steraskin
State
Liquid
Steraskin
LogP
6.941
Steraskin
Dosage Forms
Liquid
Steraskin
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Steraskin
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Steraskin
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Steraskin
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Steraskin
Patient Information
No information avaliable
Steraskin
Organisms Affected
Enteric bacteria and other eubacteria