Hexascrub
Brand names,
Hexascrub
Analogs
Hexascrub
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexascrub
Chemical_Formula
C13H6Cl6O2
Hexascrub
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexascrub
fda sheet
Hexascrub
msds (material safety sheet)
Hexascrub
Synthesis Reference
No information avaliable
Hexascrub
Molecular Weight
406.902 g/mol
Hexascrub
Melting Point
166.5 oC (boiling point)
Hexascrub
H2O Solubility
140 mg/L
Hexascrub
State
Liquid
Hexascrub
LogP
6.941
Hexascrub
Dosage Forms
Liquid
Hexascrub
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexascrub
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexascrub
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexascrub
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexascrub
Patient Information
No information avaliable
Hexascrub
Organisms Affected
Enteric bacteria and other eubacteria