Dermadex
Brand names,
Dermadex
Analogs
Dermadex
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Dermadex
Chemical_Formula
C13H6Cl6O2
Dermadex
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Dermadex
fda sheet
Dermadex
msds (material safety sheet)
Dermadex
Synthesis Reference
No information avaliable
Dermadex
Molecular Weight
406.902 g/mol
Dermadex
Melting Point
166.5 oC (boiling point)
Dermadex
H2O Solubility
140 mg/L
Dermadex
State
Liquid
Dermadex
LogP
6.941
Dermadex
Dosage Forms
Liquid
Dermadex
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Dermadex
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Dermadex
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Dermadex
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Dermadex
Patient Information
No information avaliable
Dermadex
Organisms Affected
Enteric bacteria and other eubacteria