Septisol
Brand names,
Septisol
Analogs
Septisol
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Septisol
Chemical_Formula
C13H6Cl6O2
Septisol
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Septisol
fda sheet
Septisol
msds (material safety sheet)
Septisol
Synthesis Reference
No information avaliable
Septisol
Molecular Weight
406.902 g/mol
Septisol
Melting Point
166.5 oC (boiling point)
Septisol
H2O Solubility
140 mg/L
Septisol
State
Liquid
Septisol
LogP
6.941
Septisol
Dosage Forms
Liquid
Septisol
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Septisol
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Septisol
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Septisol
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Septisol
Patient Information
No information avaliable
Septisol
Organisms Affected
Enteric bacteria and other eubacteria