HCP
Brand names,
HCP
Analogs
HCP
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
HCP
Chemical_Formula
C13H6Cl6O2
HCP
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
HCP
fda sheet
HCP
msds (material safety sheet)
HCP
Synthesis Reference
No information avaliable
HCP
Molecular Weight
406.902 g/mol
HCP
Melting Point
166.5 oC (boiling point)
HCP
H2O Solubility
140 mg/L
HCP
State
Liquid
HCP
LogP
6.941
HCP
Dosage Forms
Liquid
HCP
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
HCP
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
HCP
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
HCP
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
HCP
Patient Information
No information avaliable
HCP
Organisms Affected
Enteric bacteria and other eubacteria