Hexachlorofen
Brand names,
Hexachlorofen
Analogs
Hexachlorofen
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexachlorofen
Chemical_Formula
C13H6Cl6O2
Hexachlorofen
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexachlorofen
fda sheet
Hexachlorofen
msds (material safety sheet)
Hexachlorofen
Synthesis Reference
No information avaliable
Hexachlorofen
Molecular Weight
406.902 g/mol
Hexachlorofen
Melting Point
166.5 oC (boiling point)
Hexachlorofen
H2O Solubility
140 mg/L
Hexachlorofen
State
Liquid
Hexachlorofen
LogP
6.941
Hexachlorofen
Dosage Forms
Liquid
Hexachlorofen
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexachlorofen
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexachlorofen
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexachlorofen
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexachlorofen
Patient Information
No information avaliable
Hexachlorofen
Organisms Affected
Enteric bacteria and other eubacteria