Hexophene
Brand names,
Hexophene
Analogs
Hexophene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexophene
Chemical_Formula
C13H6Cl6O2
Hexophene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexophene
fda sheet
Hexophene
msds (material safety sheet)
Hexophene
Synthesis Reference
No information avaliable
Hexophene
Molecular Weight
406.902 g/mol
Hexophene
Melting Point
166.5 oC (boiling point)
Hexophene
H2O Solubility
140 mg/L
Hexophene
State
Liquid
Hexophene
LogP
6.941
Hexophene
Dosage Forms
Liquid
Hexophene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexophene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexophene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexophene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexophene
Patient Information
No information avaliable
Hexophene
Organisms Affected
Enteric bacteria and other eubacteria