Surofene
Brand names,
Surofene
Analogs
Surofene
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Surofene
Chemical_Formula
C13H6Cl6O2
Surofene
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Surofene
fda sheet
Surofene
msds (material safety sheet)
Surofene
Synthesis Reference
No information avaliable
Surofene
Molecular Weight
406.902 g/mol
Surofene
Melting Point
166.5 oC (boiling point)
Surofene
H2O Solubility
140 mg/L
Surofene
State
Liquid
Surofene
LogP
6.941
Surofene
Dosage Forms
Liquid
Surofene
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Surofene
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Surofene
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Surofene
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Surofene
Patient Information
No information avaliable
Surofene
Organisms Affected
Enteric bacteria and other eubacteria