Hexachlorophene, Pharma
Brand names,
Hexachlorophene, Pharma
Analogs
Hexachlorophene, Pharma
Brand Names Mixture
- Fosteen Dermatologic Shampoo (Hexachlorophene + Lanolin + Salicylic Acid + Sulfur)
- Hexaphenyl (Hexachlorophene + Isopropyl Alcohol)
Hexachlorophene, Pharma
Chemical_Formula
C13H6Cl6O2
Hexachlorophene, Pharma
RX_link
http://www.rxlist.com/cgi/generic2/hexchlorph.htm
Hexachlorophene, Pharma
fda sheet
Hexachlorophene, Pharma
msds (material safety sheet)
Hexachlorophene, Pharma
Synthesis Reference
No information avaliable
Hexachlorophene, Pharma
Molecular Weight
406.902 g/mol
Hexachlorophene, Pharma
Melting Point
166.5 oC (boiling point)
Hexachlorophene, Pharma
H2O Solubility
140 mg/L
Hexachlorophene, Pharma
State
Liquid
Hexachlorophene, Pharma
LogP
6.941
Hexachlorophene, Pharma
Dosage Forms
Liquid
Hexachlorophene, Pharma
Indication
For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Hexachlorophene, Pharma
Pharmacology
Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Hexachlorophene, Pharma
Absorption
Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Hexachlorophene, Pharma
side effects and Toxicity
Oral, rat LD50: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities.
Hexachlorophene, Pharma
Patient Information
No information avaliable
Hexachlorophene, Pharma
Organisms Affected
Enteric bacteria and other eubacteria