Pancalma

Pancalma Brand names, Pancalma Analogs

Pancalma Brand Names Mixture

No information avaliable

Pancalma Chemical_Formula

C₂₀H₂₃NS

Pancalma RX_link

No information avaliable

Pancalma fda sheet

Pancalma msds (material safety sheet)

Pancalma Synthesis Reference

No information avaliable

Pancalma Molecular Weight

309.469 g/mol

Pancalma Melting Point

< 25 ^oC

Pancalma H₂O Solubility

Soluble as HCl salt

Pancalma State

Liquid

Pancalma LogP

5.7

Pancalma Dosage Forms

Tablets (oral, 1 mg)

Pancalma Indication

Used for the symptomatic treatment of parkinsonism.

Pancalma Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Pancalma Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Pancalma side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Pancalma Patient Information

Pancalma Organisms Affected

Humans and other mammals