Meprovan

Meprovan Brand names, Meprovan Analogs

Meprovan Brand Names Mixture

No information avaliable

Meprovan Chemical_Formula

C₂₀H₂₃NS

Meprovan RX_link

No information avaliable

Meprovan fda sheet

Meprovan msds (material safety sheet)

Meprovan Synthesis Reference

No information avaliable

Meprovan Molecular Weight

309.469 g/mol

Meprovan Melting Point

< 25 ^oC

Meprovan H₂O Solubility

Soluble as HCl salt

Meprovan State

Liquid

Meprovan LogP

5.7

Meprovan Dosage Forms

Tablets (oral, 1 mg)

Meprovan Indication

Used for the symptomatic treatment of parkinsonism.

Meprovan Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Meprovan Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Meprovan side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Meprovan Patient Information

Meprovan Organisms Affected

Humans and other mammals