Calmadin
Category
Calmadin Brand names, Calmadin Analogs
Calmadin Brand Names Mixture
Calmadin Chemical_Formula
C20H23NS
Calmadin RX_link
No information avaliable
Calmadin fda sheet
Calmadin msds (material safety sheet)
Calmadin Synthesis Reference
No information avaliable
Calmadin Molecular Weight
309.469 g/mol
Calmadin Melting Point
< 25 oC
Calmadin H2O Solubility
Soluble as HCl salt
Calmadin State
Liquid
Calmadin LogP
5.7
Calmadin Dosage Forms
Tablets (oral, 1 mg)
Calmadin Indication
Used for the symptomatic treatment of parkinsonism.
Calmadin Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Calmadin Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Calmadin side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Calmadin Patient Information
Calmadin Organisms Affected
Humans and other mammals
