Meprindon

Meprindon Brand names, Meprindon Analogs

Meprindon Brand Names Mixture

No information avaliable

Meprindon Chemical_Formula

C₂₀H₂₃NS

Meprindon RX_link

No information avaliable

Meprindon fda sheet

Meprindon msds (material safety sheet)

Meprindon Synthesis Reference

No information avaliable

Meprindon Molecular Weight

309.469 g/mol

Meprindon Melting Point

< 25 ^oC

Meprindon H₂O Solubility

Soluble as HCl salt

Meprindon State

Liquid

Meprindon LogP

5.7

Meprindon Dosage Forms

Tablets (oral, 1 mg)

Meprindon Indication

Used for the symptomatic treatment of parkinsonism.

Meprindon Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Meprindon Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Meprindon side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Meprindon Patient Information

Meprindon Organisms Affected

Humans and other mammals