Placitate

Placitate Brand names, Placitate Analogs

Placitate Brand Names Mixture

No information avaliable

Placitate Chemical_Formula

C₂₀H₂₃NS

Placitate RX_link

No information avaliable

Placitate fda sheet

Placitate msds (material safety sheet)

Placitate Synthesis Reference

No information avaliable

Placitate Molecular Weight

309.469 g/mol

Placitate Melting Point

< 25 ^oC

Placitate H₂O Solubility

Soluble as HCl salt

Placitate State

Liquid

Placitate LogP

5.7

Placitate Dosage Forms

Tablets (oral, 1 mg)

Placitate Indication

Used for the symptomatic treatment of parkinsonism.

Placitate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Placitate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Placitate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Placitate Patient Information

Placitate Organisms Affected

Humans and other mammals