Sedabamate

Sedabamate Brand names, Sedabamate Analogs

Sedabamate Brand Names Mixture

No information avaliable

Sedabamate Chemical_Formula

C₂₀H₂₃NS

Sedabamate RX_link

No information avaliable

Sedabamate fda sheet

Sedabamate msds (material safety sheet)

Sedabamate Synthesis Reference

No information avaliable

Sedabamate Molecular Weight

309.469 g/mol

Sedabamate Melting Point

< 25 ^oC

Sedabamate H₂O Solubility

Soluble as HCl salt

Sedabamate State

Liquid

Sedabamate LogP

5.7

Sedabamate Dosage Forms

Tablets (oral, 1 mg)

Sedabamate Indication

Used for the symptomatic treatment of parkinsonism.

Sedabamate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Sedabamate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Sedabamate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Sedabamate Patient Information

Sedabamate Organisms Affected

Humans and other mammals