Kesso-Bamate
Category
Kesso-Bamate Brand names, Kesso-Bamate Analogs
Kesso-Bamate Brand Names Mixture
Kesso-Bamate Chemical_Formula
C20H23NS
Kesso-Bamate RX_link
No information avaliable
Kesso-Bamate fda sheet
Kesso-Bamate msds (material safety sheet)
Kesso-Bamate Synthesis Reference
No information avaliable
Kesso-Bamate Molecular Weight
309.469 g/mol
Kesso-Bamate Melting Point
< 25 oC
Kesso-Bamate H2O Solubility
Soluble as HCl salt
Kesso-Bamate State
Liquid
Kesso-Bamate LogP
5.7
Kesso-Bamate Dosage Forms
Tablets (oral, 1 mg)
Kesso-Bamate Indication
Used for the symptomatic treatment of parkinsonism.
Kesso-Bamate Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Kesso-Bamate Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Kesso-Bamate side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Kesso-Bamate Patient Information
Kesso-Bamate Organisms Affected
Humans and other mammals
