Brobamate

Brobamate Brand names, Brobamate Analogs

Brobamate Brand Names Mixture

No information avaliable

Brobamate Chemical_Formula

C₂₀H₂₃NS

Brobamate RX_link

No information avaliable

Brobamate fda sheet

Brobamate msds (material safety sheet)

Brobamate Synthesis Reference

No information avaliable

Brobamate Molecular Weight

309.469 g/mol

Brobamate Melting Point

< 25 ^oC

Brobamate H₂O Solubility

Soluble as HCl salt

Brobamate State

Liquid

Brobamate LogP

5.7

Brobamate Dosage Forms

Tablets (oral, 1 mg)

Brobamate Indication

Used for the symptomatic treatment of parkinsonism.

Brobamate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Brobamate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Brobamate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Brobamate Patient Information

Brobamate Organisms Affected

Humans and other mammals