Probamyl
Category
Probamyl Brand names, Probamyl Analogs
Probamyl Brand Names Mixture
Probamyl Chemical_Formula
C20H23NS
Probamyl RX_link
No information avaliable
Probamyl fda sheet
Probamyl msds (material safety sheet)
Probamyl Synthesis Reference
No information avaliable
Probamyl Molecular Weight
309.469 g/mol
Probamyl Melting Point
< 25 oC
Probamyl H2O Solubility
Soluble as HCl salt
Probamyl State
Liquid
Probamyl LogP
5.7
Probamyl Dosage Forms
Tablets (oral, 1 mg)
Probamyl Indication
Used for the symptomatic treatment of parkinsonism.
Probamyl Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Probamyl Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Probamyl side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Probamyl Patient Information
Probamyl Organisms Affected
Humans and other mammals
