Ataraxine
Category
Ataraxine Brand names, Ataraxine Analogs
Ataraxine Brand Names Mixture
Ataraxine Chemical_Formula
C20H23NS
Ataraxine RX_link
No information avaliable
Ataraxine fda sheet
Ataraxine msds (material safety sheet)
Ataraxine Synthesis Reference
No information avaliable
Ataraxine Molecular Weight
309.469 g/mol
Ataraxine Melting Point
< 25 oC
Ataraxine H2O Solubility
Soluble as HCl salt
Ataraxine State
Liquid
Ataraxine LogP
5.7
Ataraxine Dosage Forms
Tablets (oral, 1 mg)
Ataraxine Indication
Used for the symptomatic treatment of parkinsonism.
Ataraxine Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ataraxine Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ataraxine side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ataraxine Patient Information
Ataraxine Organisms Affected
Humans and other mammals
