Robamate

Robamate Brand names, Robamate Analogs

Robamate Brand Names Mixture

No information avaliable

Robamate Chemical_Formula

C₂₀H₂₃NS

Robamate RX_link

No information avaliable

Robamate fda sheet

Robamate msds (material safety sheet)

Robamate Synthesis Reference

No information avaliable

Robamate Molecular Weight

309.469 g/mol

Robamate Melting Point

< 25 ^oC

Robamate H₂O Solubility

Soluble as HCl salt

Robamate State

Liquid

Robamate LogP

5.7

Robamate Dosage Forms

Tablets (oral, 1 mg)

Robamate Indication

Used for the symptomatic treatment of parkinsonism.

Robamate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Robamate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Robamate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Robamate Patient Information

Robamate Organisms Affected

Humans and other mammals