Restran

Restran Brand names, Restran Analogs

Restran Brand Names Mixture

No information avaliable

Restran Chemical_Formula

C₂₀H₂₃NS

Restran RX_link

No information avaliable

Restran fda sheet

Restran msds (material safety sheet)

Restran Synthesis Reference

No information avaliable

Restran Molecular Weight

309.469 g/mol

Restran Melting Point

< 25 ^oC

Restran H₂O Solubility

Soluble as HCl salt

Restran State

Liquid

Restran LogP

5.7

Restran Dosage Forms

Tablets (oral, 1 mg)

Restran Indication

Used for the symptomatic treatment of parkinsonism.

Restran Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Restran Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Restran side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Restran Patient Information

Restran Organisms Affected

Humans and other mammals