Vistabamate
Category
Vistabamate Brand names, Vistabamate Analogs
Vistabamate Brand Names Mixture
Vistabamate Chemical_Formula
C20H23NS
Vistabamate RX_link
No information avaliable
Vistabamate fda sheet
Vistabamate msds (material safety sheet)
Vistabamate Synthesis Reference
No information avaliable
Vistabamate Molecular Weight
309.469 g/mol
Vistabamate Melting Point
< 25 oC
Vistabamate H2O Solubility
Soluble as HCl salt
Vistabamate State
Liquid
Vistabamate LogP
5.7
Vistabamate Dosage Forms
Tablets (oral, 1 mg)
Vistabamate Indication
Used for the symptomatic treatment of parkinsonism.
Vistabamate Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Vistabamate Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Vistabamate side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Vistabamate Patient Information
Vistabamate Organisms Affected
Humans and other mammals