Mepiosine
Category
Mepiosine Brand names, Mepiosine Analogs
Mepiosine Brand Names Mixture
Mepiosine Chemical_Formula
C20H23NS
Mepiosine RX_link
No information avaliable
Mepiosine fda sheet
Mepiosine msds (material safety sheet)
Mepiosine Synthesis Reference
No information avaliable
Mepiosine Molecular Weight
309.469 g/mol
Mepiosine Melting Point
< 25 oC
Mepiosine H2O Solubility
Soluble as HCl salt
Mepiosine State
Liquid
Mepiosine LogP
5.7
Mepiosine Dosage Forms
Tablets (oral, 1 mg)
Mepiosine Indication
Used for the symptomatic treatment of parkinsonism.
Mepiosine Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepiosine Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepiosine side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepiosine Patient Information
Mepiosine Organisms Affected
Humans and other mammals
