Tranquiline

Tranquiline Brand names, Tranquiline Analogs

Tranquiline Brand Names Mixture

No information avaliable

Tranquiline Chemical_Formula

C₂₀H₂₃NS

Tranquiline RX_link

No information avaliable

Tranquiline fda sheet

Tranquiline msds (material safety sheet)

Tranquiline Synthesis Reference

No information avaliable

Tranquiline Molecular Weight

309.469 g/mol

Tranquiline Melting Point

< 25 ^oC

Tranquiline H₂O Solubility

Soluble as HCl salt

Tranquiline State

Liquid

Tranquiline LogP

5.7

Tranquiline Dosage Forms

Tablets (oral, 1 mg)

Tranquiline Indication

Used for the symptomatic treatment of parkinsonism.

Tranquiline Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Tranquiline Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Tranquiline side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Tranquiline Patient Information

Tranquiline Organisms Affected

Humans and other mammals