Proquanil

Proquanil Brand names, Proquanil Analogs

Proquanil Brand Names Mixture

No information avaliable

Proquanil Chemical_Formula

C₂₀H₂₃NS

Proquanil RX_link

No information avaliable

Proquanil fda sheet

Proquanil msds (material safety sheet)

Proquanil Synthesis Reference

No information avaliable

Proquanil Molecular Weight

309.469 g/mol

Proquanil Melting Point

< 25 ^oC

Proquanil H₂O Solubility

Soluble as HCl salt

Proquanil State

Liquid

Proquanil LogP

5.7

Proquanil Dosage Forms

Tablets (oral, 1 mg)

Proquanil Indication

Used for the symptomatic treatment of parkinsonism.

Proquanil Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Proquanil Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Proquanil side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Proquanil Patient Information

Proquanil Organisms Affected

Humans and other mammals