Meprotil
Category
Meprotil Brand names, Meprotil Analogs
Meprotil Brand Names Mixture
Meprotil Chemical_Formula
C20H23NS
Meprotil RX_link
No information avaliable
Meprotil fda sheet
Meprotil msds (material safety sheet)
Meprotil Synthesis Reference
No information avaliable
Meprotil Molecular Weight
309.469 g/mol
Meprotil Melting Point
< 25 oC
Meprotil H2O Solubility
Soluble as HCl salt
Meprotil State
Liquid
Meprotil LogP
5.7
Meprotil Dosage Forms
Tablets (oral, 1 mg)
Meprotil Indication
Used for the symptomatic treatment of parkinsonism.
Meprotil Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprotil Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprotil side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprotil Patient Information
Meprotil Organisms Affected
Humans and other mammals
