Mar-Bate
Category
Mar-Bate Brand names, Mar-Bate Analogs
Mar-Bate Brand Names Mixture
Mar-Bate Chemical_Formula
C20H23NS
Mar-Bate RX_link
No information avaliable
Mar-Bate fda sheet
Mar-Bate msds (material safety sheet)
Mar-Bate Synthesis Reference
No information avaliable
Mar-Bate Molecular Weight
309.469 g/mol
Mar-Bate Melting Point
< 25 oC
Mar-Bate H2O Solubility
Soluble as HCl salt
Mar-Bate State
Liquid
Mar-Bate LogP
5.7
Mar-Bate Dosage Forms
Tablets (oral, 1 mg)
Mar-Bate Indication
Used for the symptomatic treatment of parkinsonism.
Mar-Bate Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mar-Bate Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mar-Bate side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mar-Bate Patient Information
Mar-Bate Organisms Affected
Humans and other mammals
