Metractyl
Category
Metractyl Brand names, Metractyl Analogs
Metractyl Brand Names Mixture
Metractyl Chemical_Formula
C20H23NS
Metractyl RX_link
No information avaliable
Metractyl fda sheet
Metractyl msds (material safety sheet)
Metractyl Synthesis Reference
No information avaliable
Metractyl Molecular Weight
309.469 g/mol
Metractyl Melting Point
< 25 oC
Metractyl H2O Solubility
Soluble as HCl salt
Metractyl State
Liquid
Metractyl LogP
5.7
Metractyl Dosage Forms
Tablets (oral, 1 mg)
Metractyl Indication
Used for the symptomatic treatment of parkinsonism.
Metractyl Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Metractyl Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Metractyl side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Metractyl Patient Information
Metractyl Organisms Affected
Humans and other mammals
