Calmiren
Category
Calmiren Brand names, Calmiren Analogs
Calmiren Brand Names Mixture
Calmiren Chemical_Formula
C20H23NS
Calmiren RX_link
No information avaliable
Calmiren fda sheet
Calmiren msds (material safety sheet)
Calmiren Synthesis Reference
No information avaliable
Calmiren Molecular Weight
309.469 g/mol
Calmiren Melting Point
< 25 oC
Calmiren H2O Solubility
Soluble as HCl salt
Calmiren State
Liquid
Calmiren LogP
5.7
Calmiren Dosage Forms
Tablets (oral, 1 mg)
Calmiren Indication
Used for the symptomatic treatment of parkinsonism.
Calmiren Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Calmiren Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Calmiren side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Calmiren Patient Information
Calmiren Organisms Affected
Humans and other mammals
