Apascil

Apascil Brand names, Apascil Analogs

Apascil Brand Names Mixture

No information avaliable

Apascil Chemical_Formula

C₂₀H₂₃NS

Apascil RX_link

No information avaliable

Apascil fda sheet

Apascil msds (material safety sheet)

Apascil Synthesis Reference

No information avaliable

Apascil Molecular Weight

309.469 g/mol

Apascil Melting Point

< 25 ^oC

Apascil H₂O Solubility

Soluble as HCl salt

Apascil State

Liquid

Apascil LogP

5.7

Apascil Dosage Forms

Tablets (oral, 1 mg)

Apascil Indication

Used for the symptomatic treatment of parkinsonism.

Apascil Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Apascil Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Apascil side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Apascil Patient Information

Apascil Organisms Affected

Humans and other mammals