Mepranil
Category
Mepranil Brand names, Mepranil Analogs
Mepranil Brand Names Mixture
Mepranil Chemical_Formula
C20H23NS
Mepranil RX_link
No information avaliable
Mepranil fda sheet
Mepranil msds (material safety sheet)
Mepranil Synthesis Reference
No information avaliable
Mepranil Molecular Weight
309.469 g/mol
Mepranil Melting Point
< 25 oC
Mepranil H2O Solubility
Soluble as HCl salt
Mepranil State
Liquid
Mepranil LogP
5.7
Mepranil Dosage Forms
Tablets (oral, 1 mg)
Mepranil Indication
Used for the symptomatic treatment of parkinsonism.
Mepranil Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepranil Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepranil side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepranil Patient Information
Mepranil Organisms Affected
Humans and other mammals
